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November 8, 2019

Liquid biopsies in pancreatic cancer

Vesicles

ABSTRACT Introduction: Pancreatic ductal adenocarcinoma (PDAC) is a disease of high lethality. Invasive tissue biopsies of primary or metastatic lesions remain the gold standard for diagnosis, but repeated sampling is ......

October 2, 2018

Zhang, Suisui, Huijun Dai, Lingyu Zhu, Fei Lin, Zhaokun Hu, Ren Jing, Weikang Zhang et al. "Microvesicles packaging IL-1β and TNF-α enhance lung inflammatory response to mechanical ventilation in part by induction of cofilin signaling." International immunopharmacology 63 (2018): 74-83.

Vesicles, qNano, TRPS

Microvesicles shed from pulmonary cells are capable of transferring inflammatory cargo to recipient cells nearby or in distant to enhance inflammation. Some authors believe that cofilin controls actin dynamics and ......

March 26, 2018

Bead Enhancement of EV Analysis

Vesicles, qEV

Extracellular vesicles (EVs) are recognized cancer biomarkers, however, clinical analysis has been difficult due to a lack of simple and sensitive assays. Here, we describe a bead-enhanced flow cytometry method, ......

November 1, 2017

Identification of exosomal muscle-specific miRNAs in serum of myotonic dystrophy patients relating to muscle disease progressIdentification of exosomal muscle-specific miRNAs in serum of myotonic dystrophy patients relating to muscle disease progress

Vesicles, qNano, TRPS

Myotonic dystrophy type 1 (DM1) is the most common form of adult-onset muscular dystrophy, which is characterised by progressive muscle wasting and the discovery of reliable blood-based biomarkers could be ......