Extracellular Vesicle News
Meet Extracellular Vesicle-Associated AAVs: Gene Therapy's Nanoparticle Power Couple
EV-AAVs (sometimes known as exo-AAVs) offer enhanced gene therapy potential over solo-AAVs, thanks to improved transduction and targeted delivery. Obtaining highly purified EV-AAVs is crucial, with size-exclusion chromatography (SEC) proving to be a scalable and effective method for isolation.
The Protein Paradigm: From Contaminants to the Extracellular Vesicle Corona
Albumin is a contaminant of extracellular vesicle isolates, right? New research suggests that it may actually be part of the extracellular vesicle corona.
qEV Publication Watch: Q1 2024
Check out some of the latest research employing qEV columns! A roundup of 10 articles making waves in the EV space.
qEV and MISEV2023: What You Need to Know
Everything you need to know about MISEV2023 and how to meet it when publishing your qEV research.
Understanding More With qEV10 Columns: Clinical Applications and Cell Death Regulation
Findings from five recent studies utilising the qEV10 column's benefits for important medical research.
Introducing the qEV 20 nm Series: A New Frontier of Isolation
Introducing the new qEV 20 nm Series, allowing you branch even further into the small end of the size spectrum and isolate more small particles than ever before.
From Heart to Brain: The Role of qEV Columns in Stem Cell EV Advancements
Read about the role of qEV columns in recent stem cell EV discoveries.
GMP-Ready qEV Columns Introduced for Enhanced Clinical Translation
A new tier of columns is now available: GMP-ready qEV columns.
Order Legacy Columns Today to Avoid Disappointment
An important notice about the planned phase out of qEV Legacy columns.
Which qEV Column Delivers the Purest EV Isolate?
If you want the purest EV isolate which qEV column should you pick?
To Dye or Not to Dye: Labelling Extracellular Vesicles (and Everything Else Unfortunately) with Lipophilic Dyes
A deep dive into the approaches, considerations and pitfalls of labelling EVs.
Introducing the qEV Magnetic Concentration Kit
A new approach to concentrating EVs after qEV isolation, featuring Magnetic Nanotrap® EV Capture Particles.
The Non-Vesicular Wave: Exomeres, Supermeres and Beyond
You know about extracellular vesicles, sure, but what about the new kids on the block? Exomeres and supermeres are here, and they are making a splash in the world of intercellular communication.
Building the Future of EV Isolation: A Q&A With Technology Networks
What does the future of extracellular vesicle isolation have in store, and how is Izon working towards that? Technology Networks speaks to Hans van der Voorn, CEO at Izon Science.
A Tale of Two Techniques: Comparing Size Exclusion Chromatography and Polymer Precipitation for Extracellular Vesicle Isolation
When it comes to yield, purity, expense and time commitment, does size exclusion chromatography or precipitation take the crown for EV isolation?
Are You Testing Protein Fractions in Your Extracellular Vesicle Therapeutics Studies? You Should Be.
How can you be sure that the active ingredient in your extracellular vesicle therapeutic is actually in extracellular vesicles?
Harvesting the Benefits of Plant Extracellular Vesicles
From Arabidopsis thaliana to red cabbage, the field of plant EV (and EV-like nanoparticle) research is a fast-changing world of basic biology and therapeutics. So why is methodology stuck in the past?
Next-Generation EV Separation: Izon Science and Agarose Bead Technologies Collaborate to Enhance Clinical Applications for Extracellular Vesicles
The collaborative agreement between Izon Science and ABT offers exceptional opportunities to develop solutions that aid in advancing EV research into clinical settings.
Maximising Extracellular Vesicle Output: A Small Bioreactor Goes a Long Way
A summary of work by Hisey et al. (2022) who made a huge leap forward in EV production capacity via the use of flask-based bioreactors.
Purity Matters: Why Different EV Isolation Methods Give Different Results
Has changing your isolation method changed your EV isolate bioactivity? Or perhaps even their cargo or markers? Here’s why.
Buy in Bulk: qEVoriginal Gen 2 Columns
100-packs now available for those looking to buy qEVoriginal Gen 2 columns in bulk.
Types of Extracellular Vesicles: From Exosomes to Oncosomes and Everything In Between
When is an extracellular vesicle an exosome? Turns out, probably less often than you think. Here we delve into EV subtypes and the (lack of) markers to tell them apart.
Exploring EVs from a Hospital-Derived Bacterial Pathogen With the Exoid and qEV10
A summary of work by Chiang et al. 2022, feat. qEV and TRPS for studying OMVs from a nosocomial bacterial pathogen.
Extracellular Vesicles and Preeclampsia: From Pathogenesis to Diagnostics and Therapeutics
Preeclampsia is a major contributor to premature birth. How might extracellular vesicles play a role in pathogenesis, prediction, and treatment?
Potential Applications of Reproductive Extracellular Vesicles: From Human Fertility to Agriculture and Beyond
The internal reproductive tract is a potential treasure trove of EVs for fields from assistive reproductive technologies to virology. In this article we discuss it all, from isolation to application.
Synovial Fluid Extracellular Vesicles: Footsoldiers of Inflammation?
Synovial fluid is a highly viscous biofluid containing immune cell-derived extracellular vesicles which could prove key to arthritides, but how should you isolate them? And what is already known about them?
Compare 5 Approaches to Milk EV Isolation: Findings From Morozumi et al 2021
A comparison of 5 isolation methods for milk extracellular vesicles: a summary of the findings of Morozumi et al. 2021.
From Astrocytoma to Preeclampsia: 4 Recent TRPS Articles Spanning the EV Field
Publications featuring Tunable Resistive Pulse Sensing (TRPS) from Q3, 2022.
Extracellular Vesicles From Cerebrospinal Fluid: Current State of the Research
Cerebrospinal Fluid presents unique challenges for EV isolation, which has been reflected in a lack of reproducibility in research.
Plasma Extracellular Vesicles: Does Anticoagulant Type Matter?
The methods you use for blood collection and processing will impact on the EVs that end up in your isolated sample. Here we discuss the evidence to help you make the right decisions for your research.