1. Crucial insights into microglial-derived EVs’ involvement in neuroinflammation
Santiago, J. V. et al. Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles. Molecular & Cellular Proteomics 22, 100678–100678 (2023). doi:https://pubmed.ncbi.nlm.nih.gov/37952696/
2. Plasma EVs show promise as a biomarker for osteoarthritis stage progression
Matejová, J. et al. Plasma-derived extracellular vesicle surface markers CD45, CD326 and CD56 correlate with the stage of osteoarthritis: A primary study of a novel and promising diagnostic tool of the disease. Scientific Reports 13, (2023). doi:https://doi.org/10.1038/s41598-023-47074-z
3. SEC by qEV is a favourable method for maintaining high purity after EV isolation
Chee, T., et al. Optimal isolation of extracellular vesicles from pleural fluid and profiling of their microRNA cargo. Journal of Extracellular Biology, (2023). doi:https://doi.org/10.1002/jex2.119
4. Muscle cell-derived exosomes are involved in the synchronisation of muscle and bone aging
Yin, P. et al. Deciphering immune landscape remodeling unravels the underlying mechanism for synchronized muscle and bone aging. Advanced Science (2023). doi:https://doi.org/10.1002/advs.202304084.
5. Cancer vaccines a real possibility thanks to EV tagging technology
Bhatta, R. et al. Metabolic tagging of extracellular vesicles and development of enhanced extracellular vesicle based cancer vaccines. Nature Communications 14, (2023). doi:https://doi.org/10.1038/s41467-023-43914-8
6. EV proteins may hold prognostic and diagnostic capabilities for plasma cell disorder patients (preprint)
Patrick M. Vanderboom, Yogesh Chawla, Surendra Dasari et al. Evaluating differences in the proteome within extracellular vesicles between pre- malignant and malignant plasma cell disorders, 30 November 2023, PREPRINT (Version 1) available at Research Square https://doi.org/10.21203/rs.3.rs-3673796/v1
7. Characterisation of activated macrophage derived EVs involved in periodontal disease
Lim, Y., Kim, H., Han, D. & Choi, B. Proteome and immune responses of extracellular vesicles derived from macrophages infected with the periodontal pathogen Tannerella forsythia. Journal of Extracellular Vesicles 12, (2023). doi:https://doi.org/10.1002/jev2.12381
8. Therapeutic EVs regulate pancreatic cancer genes by a qEV-mediated methodology
Chiang, C.-L. et al. Dual targeted extracellular vesicles regulate oncogenic genes in advanced pancreatic cancer. Nature Communications 14, 6692 (2023). doi:https://doi.org/10.1038/s41467-023-42402-3
9. Autism Spectrum Disorder modulated by changes in the periphery, mediated by EVs
Chen, L. et al. Blood exosome sensing via neuronal insulin-like growth factor-1 regulates autism-related phenotypes. Pharmacological Research 197, 106965–106965 (2023). doi:https://doi.org/10.1016/j.phrs.2023.106965
10. Antiviral packaged EV therapy shows promise as a COVID-19 treatment
Jayasinghe, M. K. et al. Red blood cell-derived extracellular vesicles display endogenous antiviral effects and enhance the efficacy of antiviral oligonucleotide therapy. ACS Nano 17, 21639–21661 (2023). doi:https://doi.org/10.1021/acsnano.3c06803
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