Abstract Transfusion of red cell concentrates (RCCs) is associated with increased risk of adverse outcomes that may be affected by different blood manufacturing methods and the presence of extracellular vesicles …
Linking exposures of particles released from nano-enabled products to toxicology: An integrated methodology for particle sampling, extraction, dispersion and dosing
Nano-enabled products (NEPs) represent a growing economic global market that integrates nanotechnology into our everyday lives. Increased consumer use and disposal of NEPs at their end of life has led …
Vibration-assisted optical injection of a single fluorescent sensor into a target cell
In this paper, we propose the selective adhesion and rapid injection of a fluorescent sensor into a target cell via the optical control of zeta potential and local vibration stimulus …
Nanofiltration to remove microparticles and decrease the thrombogenicity of plasma: in vitro feasibility assessment
BACKGROUND As plasma contains procoagulant microparticles (MPs), removing MPs by 75-nm nanofiltration may decrease plasma in vitro thrombogenicity while maintaining the hemostatic activity from coagulation factors. STUDY DESIGN AND METHODS …
Acoustic Cavitation-Mediated Delivery of Small Interfering Ribonucleic Acids with Phase-Shift Nano-emulsions
Localized, targeted delivery of small interfering ribonucleic acid (siRNA) has been the foremost hurdle in the use of siRNA for the treatment of various diseases. Major advances have been achieved …
Cryo-Electron Microscopy Structure of Human Peroxiredoxin-3 Filament Reveals the Assembly of a Putative Chaperone
Peroxiredoxins (Prxs) are a ubiquitous class of thiol-dependent peroxidases that play an important role in the protection and response of cells to oxidative stress. The catalytic unit of typical 2-Cys …
Biocompatible Polymer–Peptide Hybrid-Based DNA Nanoparticles for Gene Delivery
Currently, research on polymers to be used as gene delivery systems is one of the most important directions in both polymer science and biomedicine. In this report, we describe a …
Monitoring of Microalgae Lipid Accumulation System Overview
Various methods have been proposed to monitor and determine microalgae lipid content accumulation, but they are indirect, time consuming, require sample preparations, and costly treatment steps. In this work, a …
Non-targeted effects of radiation exposure:recent advances and implications
The target theory of radiation-induced effects has been challenged by numerous studies, which indicate that in addition to biological effects resulting from direct DNA damage within the cell, a variety …
The non-targeted effects of radiation are perpetuated by exosomes
Exosomes contain cargo material from endosomes, cytosol, plasma membrane and microRNA molecules, they are released by a number of non-cancer and cancer cells into both the extracellular microenvironment and body …
Emergence of tunable resistive pulse sensing as a biosensor
Abstract The article is written as a guide and tutorial that focuses on the use of Tunable Resistive Pulse Sensing, TRPS, as a platform for the detection of biological analytes. …
Monitoring bacterial growth using tunable resistive pulse sensing with a pore-based technique
A novel bacterial growth monitoring method using a tunable resistive pulse sensor (TRPS) system is introduced in this study for accurate and sensitive measurement of cell size and cell concentration …
Platelet microparticles: detection and assessment of their paradoxical functional roles in disease and regenerative medicine
There is increasing research on and clinical interest in the physiological role played by platelet microparticles (PMPs). PMPs are 0.1-1-µm fragments shed from plasma membranes of platelets that are undergoing …
Active caspase-3 is removed from cells by release of caspase-3-enriched vesicles
Cleavage of Rho associated Coiled Coil kinase I (ROCK I) by caspase-3 contributes to membrane blebbing. Whether caspase-3 and ROCK I also play a role in the release of membrane …
