Zhang, Suisui, Huijun Dai, Lingyu Zhu, Fei Lin, Zhaokun Hu, Ren Jing, Weikang Zhang et al. “Microvesicles packaging IL-1β and TNF-α enhance lung inflammatory response to mechanical ventilation in part by induction of cofilin signaling.” International immunopharmacology 63 (2018): 74-83.

In by Jules van der Voorn

Microvesicles shed from pulmonary cells are capable of transferring inflammatory cargo to recipient cells nearby or in distant to enhance inflammation. Some authors believe that cofilin controls actin dynamics and …

Strategic design of extracellular vesicle drug delivery systems

In by Jules van der Voorn

Extracellular vesicles (EVs), sub-micron vectors used in intercellular communication, have demonstrated great promise as natural drug delivery systems. Recent reports have detailed impressive in vivo results from the administration of …